When a person is diagnosed with type 2 diabetes can control their blood sugar diet alone, anti-diabetic drug miglitol, or Glyset, sometimes prescribed to slow the body’s ability to break down carbohydrates into simple sugars. It was taken at the beginning of the meal to avoid a sudden rise in blood sugar after meals. It works by inhibiting an enzyme called alpha-glucosidase.
Investigators St Marianna University School of Medicine, Kawasaki, Japan, studied the use of miglitol in Type 2 diabetes patients take multiple insulin injections per day . Their study, published in February 2012 in the Journal of Endocrinology, including 120 participants were diagnosed with type 2 diabetes.
43 diabetics receiving miglitol with insulin injections, while
81 diabetics receiving insulin alone.
Patients taking miglitol showed lower blood sugar levels in both the 1 hour and 2 hours after meals and less variation in levels of blood sugar than diabetics take insulin alone.
Another study, published in Diabetes Therapy technology in February 2012, achieving the same results. Researchers at Jikei University School of Medicine in Tokyo, Japan, studied 21 type 2 diabetic volunteers for 3 days. Within a few days of insulin given, while other days were given insulin with miglitol. Found that administration of miglitol plus insulin reduced blood sugar levels after eating more than giving insulin alone.
From this study provides Forrester miglitol with insulin to lower blood sugar levels after meals without risk of increasing the dose of insulin, which increases the risk of weight abnormally low blood sugar levels (hypoglycemia) miglitol (Glyset):. This is an anti-diabetic drug in tablet form:
Initial dose is 25 mg once daily, taken with the first bite of food, gradually increased to 25 mg three times per day.
4-8 weeks after the dose was increased to 50 mg three times a day, and can be taken with a maximum dose of 100mg three times per day.
Side effects include:
gas rising star,
so it must be taken with inflammatory bowel disease, colonic ulceration, or bowel obstruction. It’s also not recommended for patients with a history of ketoacidosis or kidney disordersOther alpha-glucosidase inhibitors include acarbose, or Precose, and voglibose. Acarbose also can cause abdominal pain, bloating, and diarrhea. The recommended dosage is usually 25mg three times per day with meals. Voglibose taken at a dose of 200-300 micrograms per day with meals.
Side effects are similar to those caused by the other two alpha-glucosidase inhibitor: abdominal bloating, abdominal distension and pain, type 2 diabetes treated with insulin diarrhea.If you (or sulfonylurea) but you still have high spiking blood sugar levels after a meal, alpha-glucosidase inhibitors may be other drugs that are good to add to your lifestyle. Why not discuss this medication with your doctor?